血清降钙素原对于慢性阻塞性肺疾病急性加重患者的临床意义

黎艳聪,舒啸.血清降钙素原对于慢性阻塞性肺疾病急性加重患者的临床意义[J].国际呼吸杂志,2013,33(5):345-347.

血清降钙素原;慢性阻塞性肺疾病急性加重;细菌感染

黎艳聪 舒啸

南方医科大学附属小榄医院呼吸内科,中山,528415

2014年

345-347

万方

目的 分析血清降钙素原在慢性阻塞性肺疾病急性加重(AECOPD)患者的表达水平及其临床意义.方法 对2012年1月至2012年5月我院收治的200例AECOPD患者进行痰液病原学、血白细胞及血清降钙素原检测及胸部影像学检查,分析其临床资料.结果 ①有细菌感染的AECOPD患者的平均血清降钙素原水平明显高于无细菌感染的AECOPD患者的平均血清降钙素原水平；②血清降钙素原在细菌感染的AECOPD患者的阳性率较血白细胞或胸部影像学检查高.结论 血清降钙素原水平升高对早期诊断AECOPD患者细菌感染有积极意义. Objective To investigate the changes and clinical implications of serum procalcitonin (PCT) in acute exacerbations of chronic obstructive pulmonary disease (AECOPD).Methods A total of 200 patients with an AECOPD were studied.On presentation,serum PCT concentrations and white bloodcell concentration were measured,and sputum culture was also performed.Furthermore,chest radiographs were taken.Results ①PCT levels were significantly higher in AECOPD patients with bacteria infection than in those without bacterial infection.② PCT had higher positive rate in AECOPD patients with bacterial infection than white blood-cell or chest radiographs.Conclusions In patients presented with AECOPD,the elevation of serum PCT has positive meaning to early diagnosis with bacterial infection.。