老年下呼吸道感染革兰阴性杆菌分布及耐药性分析

才华.老年下呼吸道感染革兰阴性杆菌分布及耐药性分析[J].吉林医学,2014,35(2):286-287.

老年人；下呼吸道感染；革兰阴性杆菌；耐药性

才华

(吉林省长春市中心医院,吉林长春130051)

2014年

286-287.

知网,万方

目的：了解老年患者下呼吸道感染革兰阴性杆菌的分布特点及耐药状况。方法：回顾性分析438例老年下呼吸道感染患者痰液细菌培养的结果,采用微量稀释法和纸片扩散法进行药敏试验。结果：从我院老年下呼吸道感染患者痰液分离培养出革兰阴性杆菌344株,其中肺炎克雷伯菌、铜绿假单胞菌、嗜麦芽窄食单胞菌、大肠埃希菌和鲍曼不动杆菌是最常见菌。敏感率最高抗菌药物的是阿米卡星82.1%；敏感率最低的抗菌药物为头孢唑啉14.8%。结论：革兰阴性杆菌为老年患者下呼吸道感染的主要病原菌,对老年患者下呼吸道感染病原菌进行连续性耐药性监测,对临床合理用药具有重要的指导意义。 ObjectiveTo investigate the distribution and antibiotic resistance from aged patientswith lower respiratory tract infections.MethodsThe gram-negative bacilli in sputum from the patients mentioned above were analyzed.Micro-dilution and disk diffusion test were used to test antimicrobial resistance.Results344 Gram-negative bacilli isolated from the aged patients.Klebsiella pneumoniae,P.aeruginosa,Stentrophomonas maltophilia,E.coli and Acinetobacter bau mannii were the most common strains among the isolates.Amikacin was showed excellent activity and cefazolin was showed minimum susceptibility against Gram-negative bacilli.ConclusionGram-negative bacilli were the most common bacterium to aged patients with lower respiratory tract infections.Monitoring of drug resistance to bacterium from aged patients with lower respiratory tract infection has an important significance to clinical treatment with drugs．。